… bronchodilators and corticosteroids, which have several contraindications, or conventional
anti-inflammatory drugs, … no exposure to genotoxic chemical agents or radiation immediately …

… drug degradants lacking publicly available genotoxicity data. Endpoints assessed in Derek
included carcinogenicity and genotoxicity … , bronchodilator, and antiasthmatic drug products …

… It showed more bronchodilator activity when compared to ileum contraction studies. GSC
exhibited equipotent spasmolytic or bronchodilator activity compared to standard drugs …

… as inflammation, diabetes, genotoxicity and cancer [19]. Piperidone … The compound may act
as bronchodilator by opposing … a bronchodilator in both histaminic and cholinergic studies. It …

… genotoxicity) induced by prophylactic or therapeutic compounds [4]; the BM is thus a target
organ for in vivo genotoxicity testing… as a part of a battery of genotoxicity tests (ICH S2). These …

… research papers on Anti-Cancer Agents … as drug candidates are highly relevant given
several studies showing those compounds’ interesting biological activities, including genotoxicity …

… , bronchodilators, coronary dilators, diuretics and anti-cancer … achieved when used as
anti-asthma treatment) was reported … , prostate and lung cancer (Hirsh et al. Citation2004). Some …

… can replace bronchodilators and decrease the dose of anti-inflammatory drugs [35]. … Also,
an anti-asthmatic effect is attributed to the presence of flavonoids which could act by inhibiting …

… effects, indicating possible bronchodilator activities or relieving … antiasthmatic effect through
leukotriene or thromboxane … not indicate antimutagenic and genotoxic activity. ese effects …

… and genotoxic … and genotoxicity did not fire any alarming alerts at the selected level of
reasoning, including key endpoints defined in Derek Nexus such as: mutagenicity, genotoxicity, …